Our laboratory focuses on understanding adipose tissue biology and systemic metabolism by studying adipose stem cells (ASC). We specifically examine ASC dynamics, the ASC niche, and the role of ASCs in white adipose tissue development, homeostasis, obesogenic expansion and thermogenesis. Using unique in vivo genetic tools, we can mark, track and manipulate these cells to gain insight into the cellular and molecular biology with the goal to elucidate possible therapies. We focus on identifying factors and nutrients that regulate and mediate ASC-niche communication, and ASC dynamics with the intent to disrupt adipocyte formation but preserve or enhance metabolic health.
Lab Members
HEATHER ROMAN
Research Support Specialist
Heather specializes in mouse genetics and cell culture modeling. Outside of work, she enjoys horseback riding, spinning and weaving, making maple syrup, and enjoying the out-of-doors on her small farm.